Cell Biology of the Axon (2009)

Description for Cell Biology of the Axon 2009

Cell Biology of the Axon
Publisher: Springer | Language: English | ISBN:3642030181 | 350 pages | Data: 2009 | PDF | 8 Mb


Description: Recent years have witnessed striking advances in research on axons at a cellular level that substantially impact our current understanding of axonal biology. Newer findings and their ramifications are critically reviewed in the 16 chapters of this volume by authors highly qualified by virtue of their scientific contributions to research areas they know and write about.

Five basic areas (I to V) germane to axonal biology are highlighted, beginning with (I) signaling interactions mediating myelination, and differentiation of axonal membrane domains; (IIa) issues surrounding organization and transport dynamics of neurofilaments in axons, (IIb) mechanisms regulating microtubule organization and dynamics, misregulation of which causes axonal degeneration, and (IIc) the roles actin binding proteins play in regulating organization and functions of the actin filament system in mature and growing axons; (IIIa) myosin motor proteins and cargoes intrinsic to the axon compartment, (IIIb) mitochondrial transport motors, and imperatives governing transport dynamics and directional delivery, (IIIc) mechanisms mediating retrograde signaling associated with NGF’s role in trophic-dependent neuronal survival, and (IIId) potential for impaired subcellular targeting of a -synuclein as a mechanism for accumulation of Lewy body inclusions in synucleinopathies; (IVa) occurrence and organization of discrete ribosome-containing domains in axons, (IVb) endogenous mRNAs, classes of proteins translated locally, and RNP trafficking in axons, (IVc) importance of locally synthesized nuclear encoded mitochondrial proteins for maintenance, function and survival of axons, (IVd) occurrence of RNA trafficking from glial cells to axons, and significance glial RNA transcripts may play in expression in axons and axon terminals, (IVe) RNA trafficking and localization of RNA transcripts in axonal growth cones, and signaling pathways that modulate local protein synthesis for directional elongation, and (IVf) genetic and molecular defects underlying spinal muscular atrophy, and roles that SMN gene product plays as a molecular chaperone in mRNA transport and translation; (Va) injury-induced local synthesis of a protein forming a retrograde signaling complex in axons to stimulate regeneration, and (Vb) endogenous and exogenous factors that condition axonal regenerative capacity in PNS and CNS, including injury-induced activation of specific genes governing regeneration.

Emergent complexities revealed in this volume compel a major revision in the traditional conceptual model of the axon’s intrinsic makeup and capacities.


Download:
Easy-Share
or
MegaUpload


ALL KIND OF MIRRORS ARE APPRECIATED!
:)
FOR MORE BIOLOGY AND MEDICAL STUFF, PLEASE - VISIT MY BLOG
THERE ARE A LOT OF INTERESTING POSTS!

Cell Biology of the Axon 2009.full.rar

Cell Biology of the Axon 2009 [TRUSTED HIGH SPEED DOWNLOAD]

Search

1. Rapidshare video-audio list page : 1289
2. Cell Biology of the Axon (Results and Problems in Cell Differentiation)
3. Endothelial Cell Culture (Handbooks in Practical Animal Cell Biology) in
4. Cell Adhesion, Volume 16 (Advances Molecular and Cell Biology) (repost)
5. Methods in Cell Biology, vol.86 - Stem Cell Culture (2008) - RE-POST!
6. Methods in Cell Biology, Volume 38: Cell Biological Applications of Confocal Microscopy
7. Mast Cell Biology: Contemporary and Emergg Topics (Advances Experimental Medice and Biology)
8. Advances in Molecular and Cell Biology, Volume 22A: Protein Structural Biology in Biomedical Research
9. Kristina Hug, "Translational Stem Cell Research: Issues Beyond the Debate on the Moral Status of the Human Embryo (Stem Cell Biology and Regenerative Medicine)"
10. Advances in Molecular and Cell Biology, Volume 32: Molecular Insights into Ion Channel Biology in Health and Disease (2004)
11. Stem Cell Biology in Health and Disease (2009)
12. International Review Of Cell and Molecular Biology, Volume 283 (International Review of Cell & Molecular Biology)
13. International Review Of Cell and Molecular Biology, Volume 284 (International Review of Cell & Molecular Biology)
14. Cell Fusion Health and Disease: II: Cell Fusion Disease (Advances Experimental Medice and Biology)
15. Methods in Cell Biology
16. Physical Biology of the Cell